Why is the combination safe? Acetaminophen and ibuprofen work differently and they’re cleared from the body by different organs. Acetaminophen can put some stress on the liver, and ibuprofen may put some stress on the stomach and kidneys, but if you’re using these drugs in safe amounts, there is minimal concern here. Pain relief for adults and children over 12 years of age. MOTRIN ® Platinum Muscle & Body’s dual action formula quickly relieves body pain, and relaxes tense muscles. Compare prices, print coupons and get savings tips for Motrin (Ibuprofen) and other Rheumatoid Arthritis, Osteoarthritis, Pain, Osteoporosis, Fever, and Menstrual Pain drugs at CVS, Walgreens, and other pharmacies. Prices start at $4.50 Over-the-counter (OTC) pain relievers can help relieve pain or lower a fever. Over-the-counter means you can buy these medicines without a prescription. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Learn more about ibuprofen, the active ingredient in MOTRIN®, and how this NSAID can help reduce fever and relieve pain for all members of your family. Treatment and Therapy - Pain Medication: Pain Medication | Intravenous Immunoglobulin | Plasmapheresis | Corticosteroids | Nerve Block | TENS | Anti-Seizure Medications | Alternative therapies | Ergonomics and Splints Motrin is used to reduce fever and treat pain or inflammation caused by headache, toothaches, back pain etc. Learn about side effects, interactions and indications. What are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)? NSAID medicines are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as: You can buy many medicines for minor problems at the store without a prescription (over-the-counter).